AP3B2 antibody (N-Term)

Catalog No. ABIN6991551

The Rabbit Polyclonal anti-AP3B2 antibody (ABIN6991551) specifically detects AP3B2 in WB, ELISA, IF and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for AP3B2 antibody (N-Term) (ABIN6991551)

Target: AP3B2 (Adaptor-Related Protein Complex 3, beta 2 Subunit (AP3B2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP3B2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-AP3B2 Antibody

Binding Specificity: N-Term

Purification: AP3B2 Antibody is affinity chromatography purified via peptide column.

Immunogen: AP3B2 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human AP3B2. The immunogen is located within the first 50 amino acids of AP3B2.

Isotype: IgG

Application Details

Application Notes: AP3B2 antibody can be used for detection of AP3B2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse and rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: AP3B2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: AP3B2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for AP3B2

Target: AP3B2 (Adaptor-Related Protein Complex 3, beta 2 Subunit (AP3B2))

Alternative Name: AP3B2

Background: AP3B2 Antibody: The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Unlike the homologous AP3B1, AP3B2-containing AP3 complexes are preferentially targeted to neuronal processes, and mice deficient in AP3B2 displayed compromised synaptic zinc stores.

Molecular Weight: Predicted: 121 kDa

Observed: 128 kDa

Gene ID: 8120

NCBI Accession: NP_001265440

UniProt: Q13367