USP10 antibody (N-Term)
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- Target See all USP10 Antibodies
- USP10 (Ubiquitin Specific Peptidase 10 (USP10))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This USP10 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- 16 amino acid peptide near the amino terminus of human USP10
- Top Product
- Discover our top product USP10 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store the antibody (in aliquots) at -20 °C.
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- Target
- USP10 (Ubiquitin Specific Peptidase 10 (USP10))
- Alternative Name
- USP10 (USP10 Products)
- Background
- USP10, also known as ubiquitin specific peptidase 10, belongs to the ubiquitin-specific protease family of cysteine proteases. USP10 functions to catalyze the cleavage of ubiquitin from ubiquitin-conjugated protein substrates such as p53/TP53, SNX3 and CFTR. USP10 has been identified as a subunit of DNA-bound androgen receptor (AR) complexes and may play a role in the activity of the DNA-bound androgen receptor complex. USP10 also acts as an essential regulator of p53/TP53 stability and is thought to function as a tumor suppressor.Synonyms: Deubiquitinating enzyme 10, KIAA0190, Ubiquitin carboxyl-terminal hydrolase 10, Ubiquitin thioesterase 10, Ubiquitin-specific-processing protease 10
- Gene ID
- 9100
- NCBI Accession
- NP_005144
- UniProt
- Q14694
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