YBX2 antibody (C-Term)
Quick Overview for YBX2 antibody (C-Term) (ABIN783693)
Target
See all YBX2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Specificity
- This antibody detects YBX2 at C-term.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse, rat
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Purification
- Affinity chromatography purified via peptide column
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Immunogen
- 18 amino acid peptide near the carboxy end of human YBX2
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- YBX2 (Y Box Binding Protein 2 (YBX2))
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Alternative Name
- YBX2
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Background
- Germ cell specific Y-box binding protein (YBX2), a germ-cell-specific member of the Y-box family of DNA-/RNA-binding proteins, is a major constituent of messenger ribonucleoprotein particles (mRNPs) and involved in the regulation of the stability and/or translation of germ cell mRNAs. It is proposed to function as a coactivator of transcription in the nucleus and to stabilize and store maternal and paternal mRNAs in the cytoplasm. YBX2 binds to the Y-box consensus promoter element and is expressed in oocytes and testicular germ cells in the stage of spermatogonia to spermatocyte. Recent studies show that deletion of YBX2 leads to the disruption of both spermatogenesis and oogenesis.Synonyms: CSDA3, Contrin, DBPC, DNA-binding protein C, Germ cell-specific Y-box-binding protein, MSY2, MSY2 homolog, Y-box-binding protein 2
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Gene ID
- 51087
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NCBI Accession
- NP_057066
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UniProt
- Q9Y2T7
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Pathways
- Chromatin Binding
Target
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