SYNPO2L antibody (N-Term)

Catalog No. ABIN783777

The Rabbit Polyclonal anti-SYNPO2L antibody (ABIN783777) specifically detects SYNPO2L in WB and EIA. The antibody is reactive with Human and Mouse samples.

Quick Overview for SYNPO2L antibody (N-Term) (ABIN783777)

Target: SYNPO2L (Synaptopodin 2-Like (SYNPO2L))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYNPO2L antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SYNPO2L Antibody

Binding Specificity: N-Term

Specificity: This antibody detects SYNPO2L at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Affinity chromatography purified via peptide column

Immunogen: Affinity chromatography purified via peptide column

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for SYNPO2L

Target: SYNPO2L (Synaptopodin 2-Like (SYNPO2L))

Alternative Name: SYNPO2L

Background: SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.Synonyms: CHAP, Synaptopodin 2-like, cytoskeletal heart-enriched actin-associated protein

Gene ID: 79933

NCBI Accession: NP_001107605

UniProt: Q9H987