SYNPO antibody (C-Term)
Quick Overview for SYNPO antibody (C-Term) (ABIN783789)
Target
See all SYNPO AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Specificity
- This antibody detects Synaptopodin / SYNPO at C-term.
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Purification
- Affinity chromatography purified via peptide column
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Immunogen
- Affinity chromatography purified via peptide column
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS, 0.02 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- SYNPO (Synaptopodin (SYNPO))
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Alternative Name
- Synaptopodin / SYNPO
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Background
- SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.Synonyms: KIAA1029
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Gene ID
- 11346
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NCBI Accession
- NP_001103444
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UniProt
- Q8N3V7
Target
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