SLC39A8
Reactivity: Human
ELISA
Host: Rabbit
Polyclonal
HRP
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Buffer
PBS containing 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Target
SLC39A8
(Solute Carrier Family 39 (Zinc Transporter), Member 8 (SLC39A8))
Alternative Name
Zinc Transporter ZIP8 / SLC39A8
Background
The zinc transporter ZIP8, also known as SLC39A9, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP8 is glycosylated and located at the plasma membrane and mitochondria. It has been identified as the transporter responsible for transport of the toxic Cadmium cation. ZIP8 has also been suggested to play a role in the regulation of interferon-gamma expression in activated human T cells.Synonyms: BCG-induced integral membrane protein in monocyte clone 103 protein, BIGM103, LIV-1 subfamily of ZIP zinc transporter 6, LZT-Hs6, Solute carrier family 39 member 8, ZIP-8, ZIP8, Zrt- and Irt-like protein 8