SLC39A13 antibody (N-Term)

Catalog No. ABIN783815

The Rabbit Polyclonal anti-SLC39A13 antibody is suitable to detect SLC39A13 in samples from Human. It has been validated for WB and EIA.

Quick Overview for SLC39A13 antibody (N-Term) (ABIN783815)

Target: SLC39A13 (Solute Carrier Family 39 (Zinc Transporter), Member 13 (SLC39A13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC39A13 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SLC39A13 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects Zinc transporter ZIP13 / SLC39A13 at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the amino terminus of human ZIP13

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for SLC39A13

Target: SLC39A13 (Solute Carrier Family 39 (Zinc Transporter), Member 13 (SLC39A13))

Alternative Name: Zinc Transporter ZIP13 / SLC39A13

Background: The zinc transporter ZIP13, also known as SLC39A13, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP13 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Mutations in ZIP13 have recently been shown to cause a spondylocheiro dysplastic form of Ehlers-Danlos syndrome (SCD-EDS), a generalized skeletal dysplasia involving mainly the spine with clinical abnormalities of the hands in addition to EDS-like features. Other experiments have shown that ZIP13 is required for proper connective tissue development and is involved in BMP/TGF- signaling pathways.Synonyms: LIV-1 subfamily of ZIP zinc transporter 9, LZT-Hs9, Solute carrier family 39 member 13, ZIP-13, ZIP13, Zrt-and Irt-like protein 13

Gene ID: 91252

NCBI Accession: NP_001121697

UniProt: Q96H72

Pathways: Transition Metal Ion Homeostasis