Adenosine A2a Receptor antibody (C-Term)

Catalog No. ABIN783921

The Goat Polyclonal anti-Adenosine A2a Receptor antibody (ABIN783921) specifically detects Adenosine A2a Receptor in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for Adenosine A2a Receptor antibody (C-Term) (ABIN783921)

Target: Adenosine A2a Receptor (ADORA2A)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Adenosine A2a Receptor antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Adenosine A2a Receptor Antibody

Binding Specificity: C-Term

Sequence: HELKGVCPEP PGLDD

Specificity: This antibody detects Adenosine A2a Receptor.

Cross-Reactivity (Details): Species reactivity (expected):Human.
Species reactivity (tested):Rhesus.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_000666.2. Genename: ADORA2A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Adenosine A2a Receptor

Target: Adenosine A2a Receptor (ADORA2A)

Alternative Name: Adenosine Receptor A2a

Background: The A2a Adenosine Receptor is a major target of caffeine. This receptor inhibits cell aggregation, induces vasodilation, and downregulates inflammation. This gene encodes a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. The encoded protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.Synonyms: ADORA2, ADORA2A

Gene ID: 135

NCBI Accession: NP_000666

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour, Cancer Immune Checkpoints