Caveolin 2 antibody (AA 1-45)

Catalog No. ABIN783942

This anti-Caveolin 2 antibody is a Rabbit Polyclonal antibody detecting Caveolin 2 in WB, IHC (p) and IF. Suitable for Human, Cow and Monkey.

Quick Overview for Caveolin 2 antibody (AA 1-45) (ABIN783942)

Target: Caveolin 2 (CAV2)

Reactivity: Human, Cow, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caveolin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-Caveolin 2 Antibody

Binding Specificity: AA 1-45

Specificity: Recognizes Caveolin-2

Cross-Reactivity (Details): Species reactivity (expected):Cow (100 %), Monkey (100 %)Species reactivity (tested):Human.

Purification: Antigen-Affinity Chromatography

Immunogen: Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human Caveolin 2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.94 mg/mL

Buffer: 0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7), 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at -20 °C.

Target Details for Caveolin 2

Target: Caveolin 2 (CAV2)

Alternative Name: Caveolin-2

Background: The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcriptSynonyms: CAV2

Molecular Weight: 18 kDa

Gene ID: 858, 9606

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development