CD163 antibody (PE)
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- Target See all CD163 Antibodies
- CD163
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD163 antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Specificity
- Monoclonal antibody 5C6 FAT recognizes a membrane glycoprotein on human monocytes and macrophages which is expressed in intermediate and late inflammatory stages. The red R-Phycoerythrin label is particularly useful to avoid the greenish autofluorescence of some cells in their resting state.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human
- Purification
- Affinity chromatography
- Immunogen
- Human CD163
- Clone
- 5C6-FAT
- Isotype
- IgG1
- Top Product
- Discover our top product CD163 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.2 mg/mL
- Buffer
- Phosphate buffered saline pH 7.2 (PBS), 0.09 % Sodium Azide, 10 mg/mL BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
- Expiry Date
- 6 months
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- Target
- CD163
- Alternative Name
- CD163 (CD163 Products)
- Background
- CD163 is a scavenger receptor for the haemoglobin-haptoglobin complex, and is upregulated by glucocorticoids and IL-10. The extracellular portion of the receptor is regularly shed and can be found in the circulation. An important function of CD163 seems to be in the adhesion of monocytes to activated endothelial cells. CD163-positive cells include skin histiocytes, Kupffer cells, spleen macrophages of the red pulp, and some thymus macrophages. The antigen is also found abundantly in human term placenta, and regularly in acute and chronic inflammatory lesions. The red R-Phycoerythrin label is particularly useful to avoid the greenish autofluorescence of some cells in their resting state.Synonyms: Hemoglobin scavenger receptor, M130, Macrophage marker, Scavenger receptor cysteine-rich type 1 protein M130
- Gene ID
- 9332
- NCBI Accession
- NP_004235
- UniProt
- Q86VB7
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