CD163 antibody (PE)

Catalog No. ABIN784617

This anti-CD163 antibody is a Mouse Monoclonal antibody detecting CD163 in FACS. Suitable for Human.

Quick Overview for CD163 antibody (PE) (ABIN784617)

Target: CD163

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD163 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 5C6-FAT

Product Details anti-CD163 Antibody (PE)

Specificity: Monoclonal antibody 5C6 FAT recognizes a membrane glycoprotein on human monocytes and macrophages which is expressed in intermediate and late inflammatory stages. The red R-Phycoerythrin label is particularly useful to avoid the greenish autofluorescence of some cells in their resting state.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography

Immunogen: Human CD163

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate buffered saline pH 7.2 (PBS), 0.09 % Sodium Azide, 10 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.

Expiry Date: 6 months

Target Details for CD163

Target: CD163

Alternative Name: CD163

Background: CD163 is a scavenger receptor for the haemoglobin-haptoglobin complex, and is upregulated by glucocorticoids and IL-10. The extracellular portion of the receptor is regularly shed and can be found in the circulation. An important function of CD163 seems to be in the adhesion of monocytes to activated endothelial cells. CD163-positive cells include skin histiocytes, Kupffer cells, spleen macrophages of the red pulp, and some thymus macrophages. The antigen is also found abundantly in human term placenta, and regularly in acute and chronic inflammatory lesions. The red R-Phycoerythrin label is particularly useful to avoid the greenish autofluorescence of some cells in their resting state.Synonyms: Hemoglobin scavenger receptor, M130, Macrophage marker, Scavenger receptor cysteine-rich type 1 protein M130

Gene ID: 9332

NCBI Accession: NP_004235

UniProt: Q86VB7