Transferrin Receptor antibody

Catalog No. ABIN784683

This anti-Transferrin Receptor antibody is a Mouse Monoclonal antibody detecting Transferrin Receptor in FACS. Suitable for Human and Monkey.

Quick Overview for Transferrin Receptor antibody (ABIN784683)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Transferrin Receptor antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: DF1513

Product Details anti-Transferrin Receptor Antibody

Specificity: This antibody recognizes the CD71 cell surface antigen, a 190 kDa homodimeric glycoprotein expressed by proliferating cells. CD71 acts as Receptor for Transferrin. Cross reacts with Rhesus Monkey, Mustelid.

Purification: Affinity Chromatography on Protein G

Endotoxin Level: Low Endotoxin

Immunogen: KG1 cell line. Remarks: Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSI myeloma cell line.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS without preservatives

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Target Details for Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name: CD71 / TFRC

Background: The transferrin receptor has been structurally characterized as a sulfide bound dimer of identical glycoprotein subunits of 95 kDa. The transferrin receptor is not present on resting blood lymphocytes. On PBL, the receptor appears after activation. The expression of transferrin receptor is coordinately regulated with cell growth. Present on T and B cell lines. The soluble (or serum) transferrin receptor (sTfR) is a circulating truncated form of the membrane receptor protein, it is an 85 kDa glycoprotein forming in serum a 320 kDa complex with diferric transferrin.The most important clinical use of the sTfR determination is in the differential diagnosis between iron deficiency anaemia and the anaemia of chronic disease.Synonyms: TfR1, Transferrin receptor protein 1, p90

Gene ID: 7037

NCBI Accession: NP_001121620

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis