Inhibin alpha antibody

Catalog No. ABIN865517

The Mouse Monoclonal anti-Inhibin alpha antibody is suitable to detect Inhibin alpha in samples from Human and Mouse. It has been validated for WB, ELISA and IF.

Quick Overview for Inhibin alpha antibody (ABIN865517)

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Inhibin alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 4E2

Product Details anti-Inhibin alpha Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human INHA expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: WB: 1/500 - 1/2000, IF: 1/200-1/1000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100g/100l

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for Inhibin alpha

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Alternative Name: INHA

Background: Inhibins are peptide hormones produced by the granulosa cells in female follicles and by Sertoli cells in the male seminiferous tubules. They are selectively expressed by cells of sex cord stromal derivation, and inhibit the secretion of follitropin by the pituitary gland. Inhibins are also involved in regulating diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins, as inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibin has 2 subunits (alpha and beta) that are coded by separate genes. The alpha subunit determines whether inhibin or activin will be produced. The alpha subunit remains constant, such that the various types of inhibin are defined by the beta subunit (a,b,c,d). Synonyms: INHA

Molecular Weight: 40kDa

Gene ID: 3623

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion