CD86 antibody

Catalog No. ABIN865523

The Mouse Monoclonal anti-CD86 antibody is suitable to detect CD86 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for CD86 antibody (ABIN865523)

Target: CD86

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD86 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1B3

Product Details anti-CD86 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human EIF2AK3 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100g/100l

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD86

Target: CD86

Alternative Name: CD86

Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. Tissue specificity: Expressed by activated B-lymphocytes and monocytes. Synonyms: B70, B7-2, LAB72, CD28LG2, MGC34413, CD86

Molecular Weight: 52kDa

Gene ID: 942

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation