The Rabbit Polyclonal anti-Calcitonin antibody (ABIN866052) specifically detects Calcitonin in WB and ICC.
The antibody is reactive with Mouse samples.
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of N-terminal residues of mouse Calcitonin.
Cross-Reactivity
Mouse (Murine)
Characteristics
Positive Control: MCF-7. Cellular Localization: Secretion protein
Calca
Reactivity: Various Species
WB, IHC, IP, ICC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB: 1:100-500. ICC: 1:250
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5mg/ml
Buffer
1xTBS (pH7.4), 0.5% BSA, 25% Glycerol
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Target
Calcitonin (Calca)
Alternative Name
Calcitonin
Background
Calcitonin is a 32 amino acid polypeptide hormone that causes a rapid but short-lived drop in the level of calcium and phosphate in the blood, by promoting the incorporation of these ions in the bones, alpha type. Alternative splicing of the gene coding for calcitonin produces a distantly related peptide of 37 amino acids, called calcitonin gene-related peptide (CGRP), beta type. Calcitonin staining is used in the identification of C cell proliferative abnormalities, such as C cell hyperplasia and invasive tumors. Staining for calcitonin can be also used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors.