ErbB2/Her2 antibody (C-Term)

Catalog No. ABIN870539

The Rabbit Monoclonal anti-ErbB2/Her2 antibody has been validated for IHC (p). It is suitable to detect ErbB2/Her2 in samples from Human.

Quick Overview for ErbB2/Her2 antibody (C-Term) (ABIN870539)

Target: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ErbB2/Her2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: A24-V

Product Details anti-ErbB2/Her2 Antibody

Binding Specificity: AA 1233-1254, C-Term

Purpose: Anti-CerbB-2

Specificity: CerbB

Immunogen: Peptide derived from C-terminal region of human C-erbB-2. Antibody recognizes the epitope between Pro1233 - Pro1254.

Isotype: IgG

Application Details

Application Notes: 1:100-1:300

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: +2 °C to +8 °C

Target Details for ErbB2/Her2

Target: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Alternative Name: HER2

Background: Also known as Her-2/neu, this protein marker is often overexpressed in breast cancer. The IHC-P bioptic examination often offers the predictive and prognostic information.

UniProt: P04626

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development