Complement C4d antibody (Internal Region)

Catalog No. ABIN870587

Product Details anti-Complement C4d Antibody

Target: Complement C4d (C4d) (Complement Component C4d (C4d))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Complement C4d antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: C4d complement

Immunogen: Peptide derived from internal sequence of human C4.

Clone: A24-T

Isotype: IgG

Application Details

Application Notes: 1:100 - 200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/ml BSA, Preservative: 0.05% sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: +2 °C to +8 °C

Target Details for Complement C4d

Target: Complement C4d (C4d) (Complement Component C4d (C4d))

Alternative Name: C4d complement (C4d Products)

Background: C4d is a split product of the complement C4 and its deposition serves as a sensitive and specific marker for antibody mediated rejection (AMR) of the transplanted organs. AMR is one of the most important adverse events after organ transplantation and if untreated, leads to significant graft loss. During AMR, C4d binds covalently to the target structures, which makes it easy to detect with corresponding antibodies. Currently, all renal transplant biopsies and biopsies from other organs as well, are required to stain with C4d antibody.

UniProt: P0C0L4