GPC4 antibody (AA 220-233)

Catalog No. ABIN870843

The Rabbit Polyclonal anti-GPC4 antibody has been validated for WB and IHC. It is suitable to detect GPC4 in samples from Human.

Quick Overview for GPC4 antibody (AA 220-233) (ABIN870843)

Target: GPC4 (Glypican 4 (GPC4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GPC4 Antibody

Binding Specificity: AA 220-233

Specificity: Specific for a core protein epitope (aa220-233) of human glypi-can- 4. Glypican-4, previously known as K-glypican, is a GPI-linked cell surface heparan sulfate proteoglycan of the glypican gene family, that comprises 6 members at present. Its function is only partially understood at present. However, glypican-4 seems to be involved in the control of cell growth and diffe-rentiation, especially in the development of the central nervous system and the kidney. Furthermore, glypican-4 is expressed by hematopoetic stem cells and bone marrow stromal cells. Although the antiserum was prepared against a peptide from human glypican-4, due to the highly conserved structure and sequence of glypican-4, it might react also with glypican-4 from other species, like mouse.

Immunogen: Synthetic glypican-4 peptide (aa220-233, -TFAQGLAVAG-DVV-) coupled to KLH (keyhole limpet haemocyanin)

Application Details

Application Notes: Westernblot (1:1000), Immunohistochemistry (1:1000) This antibody has not been tested for use in all applications. This does not necessarily exclude its use for non-tested procedures. The stated dilutions are recommendations only.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Resuspend in aqua bidest.

Storage: 4 °C

Target Details for GPC4

Target: GPC4 (Glypican 4 (GPC4))

Alternative Name: Glypican-4

UniProt: O75487

Pathways: Glycosaminoglycan Metabolic Process