CARD17 antibody (AA 1-100)

Catalog No. ABIN872386

This Rabbit Polyclonal antibody specifically detects CARD17 in WB, ELISA, IF (cc), IF (p), IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CARD17 antibody (AA 1-100) (ABIN872386)

Target: CARD17 (Caspase Recruitment Domain Family, Member 17 (CARD17))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARD17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CARD17 Antibody

Binding Specificity: AA 1-100

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CARD17/INCA

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CARD17

Target: CARD17 (Caspase Recruitment Domain Family, Member 17 (CARD17))

Alternative Name: CARD17

Background:

Synonyms: CAR17_HUMAN, CARD 17, CARD17, Caspase 1 inhibitor, Caspase recruitment domain containing protein 17, Caspase recruitment domain-containing protein 17, Caspase-1 inhibitor INCA, Caspase1 inhibitor, Inhibitory caspase recruitment domain CARD protein, Inhibitory caspase recruitment domain protein.

Background: Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.