TIAF1 antibody (AA 34-115)

Catalog No. ABIN872387

The Rabbit Polyclonal anti-TIAF1 antibody has been validated for ELISA, IF (cc), IF (p), IHC (fro) and IHC (p). It is suitable to detect TIAF1 in samples from Human.

Quick Overview for TIAF1 antibody (AA 34-115) (ABIN872387)

Target: TIAF1 (TGFB1-Induced Anti-Apoptotic Factor 1 (TIAF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIAF1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TIAF1 Antibody

Binding Specificity: AA 34-115

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TIAF1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TIAF1

Target: TIAF1 (TGFB1-Induced Anti-Apoptotic Factor 1 (TIAF1))

Alternative Name: TIAF1

Background:

Synonyms: MAJN, TGFB1 induced anti apoptotic factor 1 12 kDa TGF beta1 induced antiapoptotic factor, TGFB1 induced anti apoptotic factor 1, TIAF1_HUMAN.

Background: TIAF-1 (TGF Beta 1-induced antiapoptotic factor 1), also known as MYO18A, MAJN or MYSPDZ, is a TGF Beta 1-induced anti-apoptotic factor that localizes to the nucleus and functions to inhibit the cytotoxic effects of TNF? TRADD and FADD. Two isoforms of mouse TIAF-1 exist and are designated MysPDZ-Alpha and MysPDZ-Beta. MysPDZ-Alpha consists of a KE-rich region, an N-terminal PDZ domain and a prevalent myosin homologous head region, while the MysPDZ-Beta isoform lacks the KE-rich region and PDZ domain. MysPDZ-Alpha is present in most tissues and is known to co-localize with the ER-Golgi complex and with membrane ruffles and filopodia. MysPDZ-Beta is expressed specifically in hematopoietic tissues and cell lines and shows dispersed localization in the cytoplasm.

Gene ID: 9220