Factor VIII antibody (AA 85-190)

Catalog No. ABIN872493

This anti-Factor VIII antibody is a Rabbit Polyclonal antibody detecting Factor VIII in ELISA, IF (p), IF (cc), IHC (p) and IHC (fro). Suitable for Human, Mouse and Rat. This Primary Antibody has been cited in 4+ publications.

Quick Overview for Factor VIII antibody (AA 85-190) (ABIN872493)

Target: Factor VIII (F8) (Coagulation Factor VIII (F8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Factor VIII antibody is un-conjugated

Application: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Factor VIII Antibody

Binding Specificity: AA 85-190

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Factor VIII

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Factor VIII antibody (ABIN872493)

Zhu, Hua, Zhu, Li, Wang, Yu, Li: "Stereoselective Regulation of P-gp Activity by Clausenamide Enantiomers in Caco-2, KB/KBv and Brain Microvessel Endothelial Cells." in: PLoS ONE, Vol. 10, Issue 8, pp. e0135866, (2016) (PubMed).

Tang, Liu, Dong, Li, Li, Hou, Zheng, Lin, Ren: "Protective Effect of Kaempferol on LPS plus ATP-Induced Inflammatory Response in Cardiac Fibroblasts." in: Inflammation, (2014) (PubMed).

Zhao, Li, Katzenellenbogen, Lau, Taylor, Bagchi, Bagchi: "Estrogen-Induced CCN1 is Critical for Establishment of Endometriosis-like Lesions in Mice." in: Molecular endocrinology (Baltimore, Md.), pp. me20141080, (2014) (PubMed).

Ning, Sun, Hong, Liang, Liu, Han, Liu, Shi, Li, Gong, Zhang, Chen, Guo, Cheng, Wu, Fan: "Calcyclin-binding protein inhibits proliferation, tumorigenicity, and invasion of gastric cancer." in: Molecular cancer research : MCR, Vol. 5, Issue 12, pp. 1254-62, (2008) (PubMed).

Target Details for Factor VIII

Target: Factor VIII (F8) (Coagulation Factor VIII (F8))

Alternative Name: Factor 8

Background:

Synonyms: AHF, F8B, F8C, HEMA, FVIII, DXS1253E, Coagulation factor VIII, Antihemophilic factor, Procoagulant component, F8

Background: Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.

Gene ID: 2157

UniProt: P00451