CDCA3 antibody (AA 201-268)

Catalog No. ABIN872629

Product Details anti-CDCA3 Antibody

Target: CDCA3 (Cell Division Cycle Associated 3 (CDCA3))

Binding Specificity: AA 201-268

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDCA3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CDCA3 antibody (ABIN872629)

Wang, Wei, Xiao, Xue, Du, Liu, Xie: "Methamphetamine induces hepatotoxicity via inhibiting cell division, arresting cell cycle and activating apoptosis: In vivo and in vitro studies." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 105, pp. 61-72, (2017) (PubMed).

Target Details for CDCA3

Target: CDCA3 (Cell Division Cycle Associated 3 (CDCA3))

Alternative Name: CDCA3 (CDCA3 Products)

Synonyms: grcc8 antibody, tome-1 antibody, GRCC8 antibody, TOME-1 antibody, 2410005A12Rik antibody, C8 antibody, Grcc8 antibody, Tome-1 antibody, cell division cycle associated 3 antibody, CDCA3 antibody, cdca3 antibody, Cdca3 antibody

Background:

Synonyms: CDCA 3, Cell division cycle associated 3, Cell division cycle associated protein 3, Gene rich cluster C8, Gene rich cluster protein C8, GRCC 8, GRCC8, MGC2577, TOME 1, TOME1, Trigger of mitotic entry 1, C8 antibody, Trigger of mitotic entry protein 1, CDCA3_HUMAN .

Background: CDCA3 (Cell division cycle associated 3) is an F-box-like protein which is required for entry into mitosis. It is associated with SKP1 as part of a SCF (SKP1-cullin-F-box) protein ligase complex, and is required for the ubiquitination and degradation of the CDK1 inhibitory tyrosine kinase WEE1 at G2/M phase.

Gene ID: 83461