TNMD antibody (AA 151-250)

Catalog No. ABIN872740

This Rabbit Polyclonal antibody specifically detects TNMD in WB, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It exhibits reactivity toward Human, Mouse and Rat and has been mentioned in 2+ publications.

Quick Overview for TNMD antibody (AA 151-250) (ABIN872740)

Target: TNMD (Tenomodulin (TNMD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNMD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TNMD Antibody

Binding Specificity: AA 151-250

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TNMD

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TNMD antibody (ABIN872740)

Wada, Ideno, Shimada, Kamiunten, Nakamura, Nakashima, Kimura, Shinkai, Tachibana, Nifuji: "H3K9MTase G9a is essential for the differentiation and growth of tenocytes in vitro." in: Histochemistry and cell biology, Vol. 144, Issue 1, pp. 13-20, (2015) (PubMed).

Shimada, Wada, Inoue, Ideno, Kamiunten, Komatsu, Kudo, Nakamura, Sato, Nakashima, Nifuji: "Efficient expansion of mouse primary tenocytes using a novel collagen gel culture method." in: Histochemistry and cell biology, Vol. 142, Issue 2, pp. 205-15, (2014) (PubMed).

Target Details for TNMD

Target: TNMD (Tenomodulin (TNMD))

Alternative Name: TNMD

Background:

Synonyms: TEM, CHM1L, BRICD4, Tenomodulin, hTeM, Chondromodulin-1-like protein, hChM1L, Chondromodulin-I-like protein, Myodulin, Tendin, TNMD, UNQ771/PRO1565

Background: Tenomodulin is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated.

Gene ID: 64102

UniProt: Q9H2S6