CCDC104 antibody (AA 241-342)

Catalog No. ABIN872777

The Rabbit Polyclonal anti-CCDC104 antibody has been validated for ELISA, IF (cc), IF (p), IHC (fro) and IHC (p). It is suitable to detect CCDC104 in samples from Human.

Quick Overview for CCDC104 antibody (AA 241-342) (ABIN872777)

Target: CCDC104 (Coiled-Coil Domain Containing 104 (CCDC104))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC104 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CCDC104 Antibody

Binding Specificity: AA 241-342

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC104

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CCDC104

Target: CCDC104 (Coiled-Coil Domain Containing 104 (CCDC104))

Alternative Name: CCDC104

Background:

Synonyms: CC104_HUMAN, CCDC104, Coiled coil domain containing 104, Coiled-coil domain-containing protein 104, MGC15407.

Background: CCDC104 is a 342 amino acid protein that exists as two alternatively spliced isoforms. CCDC104 undergoes post-translational phosphorylation following DNA damage, most likely by either ATR or ATM. The gene encoding CCDC104 maps to human chromosome 2, the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene.

Gene ID: 112942