BCL2L13 antibody (AA 281-380)

Catalog No. ABIN872935

This Rabbit Polyclonal antibody specifically detects BCL2L13 in WB, ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for BCL2L13 antibody (AA 281-380) (ABIN872935)

Target: BCL2L13 (BCL2-Like 13 (Apoptosis Facilitator) (BCL2L13))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL2L13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-BCL2L13 Antibody

Binding Specificity: AA 281-380

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Dog,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Bcl rambo/Bcl 2 like 13 protein

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for BCL2L13

Target: BCL2L13 (BCL2-Like 13 (Apoptosis Facilitator) (BCL2L13))

Alternative Name: Bcl 2 like 13 protein

Background:

Synonyms: Apoptosis facilitator, Bcl 2 like 13, Bcl 2 like 13 protein, BCL2 like 13 apoptosis facilitator, BCL2 like 13, Bcl2 like 13 protein, BCL2L13, MIL 1, MIL1, MIL1 protein, Protein Mil1, B2L13_HUMAN.

Background: Bcl rambo shares common structural characteristics with other members of the anti-apoptotic Bcl2 family members, but differs from them at its C-terminus, where a 250 amino acid sequence preceeds the membrane anchor region. It also differs from other pro-apoptotic Bcl-2 family members in that its membrane anchor C-terminus region is responsible for its apoptotic activity, not its Bcl-2 homology motifs. Bcl rambo may promote the activation of caspase-3 and apoptosis.

Gene ID: 23786

UniProt: Q9BXK5

Pathways: Positive Regulation of Endopeptidase Activity