AGFG1 antibody (AA 276-380)

Catalog No. ABIN872992

This Rabbit Polyclonal antibody specifically detects AGFG1 in WB, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for AGFG1 antibody (AA 276-380) (ABIN872992)

Target: AGFG1 (HRB) (HIV-1 Rev Binding Protein (HRB))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGFG1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-AGFG1 Antibody

Binding Specificity: AA 276-380

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AGFG1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for AGFG1

Target: AGFG1 (HRB) (HIV-1 Rev Binding Protein (HRB))

Alternative Name: AGFG1

Background:

Synonyms: HIV 1 Rev binding protein, RAB, Rev/Rex activation domain-binding protein, RIP, AGFG1, AGFG1_HUMAN, Arf-GAP domain and FG repeats-containing protein 1, ArfGAP with FG repeats 1, HIV-1 Rev-binding protein, HRB, Nucleoporin like protein RIP, Nucleoporin-like protein RIP, Rev interacting protein, Rev-interacting protein.

Background: Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.