CLPTM1L antibody (AA 165-270)

Catalog No. ABIN873033

This anti-CLPTM1L antibody is a Rabbit Polyclonal antibody detecting CLPTM1L in ELISA, IHC (p), ICC, IF (cc), IF (p) and IHC (fro). Suitable for Human.

Quick Overview for CLPTM1L antibody (AA 165-270) (ABIN873033)

Target: CLPTM1L (CLPTM1-Like (CLPTM1L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLPTM1L antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CLPTM1L Antibody

Binding Specificity: AA 165-270

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLPTM1L/CRR9

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CLPTM1L

Target: CLPTM1L (CLPTM1-Like (CLPTM1L))

Alternative Name: CRR9

Background:

Synonyms: Cisplatin resistance related protein 9, Cisplatin resistance related protein CRR9p, Cisplatin resistance-related protein 9, Cleft lip and palate transmembrane protein 1 like protein, Cleft lip and palate transmembrane protein 1-like protein, CLP1L_HUMAN, CLPTM1 like, CLPTM1 like protein, CLPTM1-like protein, CLPTM1L, CRR9, CRR9p.

Background: Clefts of the oral-facial region usually occur in early fetal development and can affect the lip, the soft palate and the hard palate. Cleft lip (with or without cleft palate) is a genetically complex birth defect that occurs in approximately one in every 750-1,000 live births. This is one of the most common birth defects and is multifactorial, with both genetic and environmental causes. Cleft lip- and palate-associated transmembrane protein 1 (CLPTM1) belongs to a family of cleft lip and palate transmembrane proteins. This family also contains cisplatin resistance-related protein (CRR9), which is involved in CDDP-induced apoptosis. CLPTM1L (cleft lip and palate transmembrane protein 1-like protein), also known as CRR9p (cisplatin resistance-related protein 9) is a 538 amino acid multi-pass membrane protein that belongs to the CLPTM1 family and, when overexpressed, enhances cisplatin-mediated apoptosis. CLPTM1L exists as two alternatively spliced isoforms encoded by a gene that maps to human chromosome 5p15.33.

Gene ID: 81037