NOG antibody (AA 28-130)

Catalog No. ABIN873145

This Rabbit Polyclonal antibody specifically detects NOG in WB, ELISA, FACS, IF (cc), IF (p), IHC (p) and IHC (fro). It exhibits reactivity toward Mouse and Ratand has been mentioned in 1 publication.

Quick Overview for NOG antibody (AA 28-130) (ABIN873145)

Target: NOG (Noggin (NOG))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NOG Antibody

Binding Specificity: AA 28-130

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Noggin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-NOG antibody (ABIN873145)

Song, Cui, Yu, Liu, Liu, Yang, He, Zhang: "Expression characteristics of BMP2, BMPR-IA and Noggin in different stages of hair follicle in yak skin." in: General and comparative endocrinology, Vol. 260, pp. 18-24, (2017) (PubMed).

Target Details for NOG

Target: NOG (Noggin (NOG))

Alternative Name: Noggin

Background:

Synonyms: NOG, NOGG_HUMAN, Noggin, SYM 1, SYM1, Symphalangism 1 proximal, Synostoses multiple syndrome 1, SYNS 1, SYNS1.

Background: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 (PubMed:21976273).

Gene ID: 9241

UniProt: Q13253

Pathways: Stem Cell Maintenance, Tube Formation