ASMT antibody

Catalog No. ABIN873275

The Rabbit Polyclonal anti-ASMT antibody has been validated for WB, ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). It is suitable to detect ASMT in samples from Human, Mouse and Rat. There are 3+ publications available.

Quick Overview for ASMT antibody (ABIN873275)

Target: ASMT (Acetylserotonin O-Methyltransferase (ASMT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASMT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ASMT Antibody

Cross-Reactivity: Rat, Sheep

Predicted Reactivity: Human,Mouse,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Acetylserotonin O-methyltransferase (ASMT)

Isotype: IgG

Application Details

Application Notes: IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-ASMT antibody (ABIN873275)

Herman, Bochenek, Król, Krawczyńska, Antushevich, Pawlina, Herman, Romanowicz, Tomaszewska-Zaremba: "Central Interleukin-1�� Suppresses the Nocturnal Secretion of Melatonin." in: Mediators of inflammation, Vol. 2016, pp. 2589483, (2017) (PubMed).

Herman, Wojtulewicz, Bochenek, Krawczyńska, Antushevich, Pawlina, Zielińska-Górska, Herman, Romanowicz, Tomaszewska-Zaremba: "Endotoxin-induced inflammation disturbs melatonin secretion in ewe." in: Asian-Australasian journal of animal sciences, Vol. 30, Issue 12, pp. 1784-1795, (2017) (PubMed).

Herman, Bochenek, Skipor, Król, Krawczyńska, Antushevich, Pawlina, Marciniak, Tomaszewska-Zaremba: "Interleukin-1 β Modulates Melatonin Secretion in Ovine Pineal Gland: Ex Vivo Study." in: BioMed research international, Vol. 2015, pp. 526464, (2016) (PubMed).

Target Details for ASMT

Target: ASMT (Acetylserotonin O-Methyltransferase (ASMT))

Alternative Name: Asmt

Background:

Synonyms: Acetylserotonin O-methyltransferase, ASMT, ASMTY, HIOMT, HIOMTY, Hydroxyindole O-methyltransferase.

Background: This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Isoform 2 and isoform 3 lack enzyme activity

Gene ID: 438

UniProt: P46597