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Insulin antibody (INS) (Alexa Fluor 555) Primary Antibody

INS Reactivity: Human IF (cc), IF (p) Host: Mouse Monoclonal 1G11 Alexa Fluor 555
Catalog No. ABIN873422
$442.20
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target
    Insulin (INS)
    Reactivity
    • 260
    • 152
    • 136
    • 121
    • 94
    • 67
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 189
    • 98
    • 23
    • 3
    • 2
    • 1
    Mouse
    Clonality
    • 193
    • 124
    Monoclonal
    Conjugate
    • 153
    • 24
    • 15
    • 11
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    This Insulin antibody is conjugated to Alexa Fluor 555
    Application
    • 105
    • 100
    • 96
    • 83
    • 74
    • 74
    • 72
    • 39
    • 26
    • 25
    • 22
    • 21
    • 20
    • 15
    • 15
    • 12
    • 10
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Purification
    Purified by Protein G.
    Immunogen
    Recombinant human Insulin protein
    Clone
    1G11
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 4 °C
    Expiry Date
    12 months
  • Target
    Insulin (INS)
    Alternative Name
    Insulin (INS Antibody Abstract)
    Synonyms
    ins1, xins, ins1-a, Insulin, IDDM2, ILPR, IRDN, MODY10, AA986540, Ins-2, InsII, Mody, Mody4, proinsulin, zgc:109842, insulin, insulin precursor, insulin II, preproinsulin, ins, PIN, INS, Ins, INS-IGF2, Ins2
    Background

    Insulin is a pancreatic hormone that regulates glucose and is involved in the synthesis of protein and fat. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Heterodimer of a B chain and an A chain linked by two disulfide bonds.Belongs to the insulin family. The insulin-link growth factors, IGF-I and IGF-II (also desinated somatomedin C and multiplication stimulating activator, respectvely), share approximatly 76 % sequence identity and are 50 % related to pro-insulin.IGF-I and IGF-II are nonglycosylated, single chain proteins of 70 and 76 amino acids in length, respectivelly. IGF-I functions as an autocrine regulator of growth in vaious, whereas the function of IGF-II is less well defined.

    Synonyms: ILPR, INS, Insulin A chain, Insulin B chain, Insulin A chain, Insulin precursor, IRDN, Proinsulin, Proinsulin precursor, IDDM2, INS_HUMAN, MODY10.

    Gene ID
    3630
    Pathways
    NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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