AQP2 antibody (pSer269) (AbBy Fluor® 647)

Catalog No. ABIN875231

The Rabbit Polyclonal anti-AQP2 antibody has been validated for WB, IF (p) and IF (cc). It is suitable to detect AQP2 in samples from Rat.

Quick Overview for AQP2 antibody (pSer269) (AbBy Fluor® 647) (ABIN875231)

Target: AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AQP2 antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-AQP2 Antibody (AbBy Fluor® 647)

Binding Specificity: pSer269

Cross-Reactivity: Rat

Predicted Reactivity: Mouse,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from mouse AQP2 around the phosphorylation site of Ser269

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for AQP2

Target: AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

Alternative Name: AQP2

Background:

Synonyms: ADH water channel, AQP 2, AQP CD, AQP2, AQPCD, Aquaporin 2 collecting duct, Aquaporin CD, Aquaporin2, Aquaporine 2, Collecting duct water channel protein, MGC34501, Water channel protein for renal collecting duct, WCH CD, WCHCD.

Background: This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant, and recessive forms of nephrogenic diabetes insipidus. Belongs to the MIP/aquaporin (TC 1.A.8) family.

Gene ID: 359

Pathways: Response to Water Deprivation