SNRPE antibody (pSer365) (AbBy Fluor® 647)

Catalog No. ABIN875770

This Rabbit Polyclonal antibody specifically detects SNRPE in IF (cc) and IF (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for SNRPE antibody (pSer365) (AbBy Fluor® 647) (ABIN875770)

Target: SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNRPE antibody is conjugated to AbBy Fluor® 647

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SNRPE Antibody (AbBy Fluor® 647)

Binding Specificity: pSer365

Specificity: This phophorylation site is homologous to that of Ser348 in Mouse and Ser347 in Rat.

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human B Raf around the phosphorylation site of Ser365

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SNRPE

Target: SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

Alternative Name: B-Raf

Background:

Synonyms: NS7, BRAF1, RAFB1, B-RAF1, Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1, BRAF

Background: Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway.

Gene ID: 673

UniProt: P15056

Pathways: Ribonucleoprotein Complex Subunit Organization, Hepatitis C