HDAC8 antibody (pSer39) (AbBy Fluor® 488)

Catalog No. ABIN875942

The Rabbit Polyclonal anti-HDAC8 antibody has been validated for IF (cc) and IF (p). It is suitable to detect HDAC8 in samples from Human.

Quick Overview for HDAC8 antibody (pSer39) (AbBy Fluor® 488) (ABIN875942)

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC8 antibody is conjugated to AbBy Fluor® 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-HDAC8 Antibody (AbBy Fluor® 488)

Binding Specificity: pSer39

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human HDAC8 around the phosphorylation site of Ser39

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HDAC8

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Alternative Name: HDAC8

Background:

Synonyms: HDAC8 Ser39, HD 8, HD8, HDAC 8, HDACL 1, HDACL1, Histone deacetylase 8, Histone deacetylase like 1, RPD 3, RPD3.

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.

Gene ID: 55869

Pathways: Cellular Glucan Metabolic Process