Ezrin antibody (pThr567) (AbBy Fluor® 555)

Catalog No. ABIN878380

This Rabbit Polyclonal antibody specifically detects Ezrin in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Ezrin antibody (pThr567) (AbBy Fluor® 555) (ABIN878380)

Target: Ezrin (EZR)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ezrin antibody is conjugated to AbBy Fluor® 555

Application: Western Blotting (WB)

Product Details anti-Ezrin Antibody (AbBy Fluor® 555)

Binding Specificity: pThr567

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Ezrin around the phosphorylation site of Thr567

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Ezrin

Target: Ezrin (EZR)

Alternative Name: Ezrin

Background:

Synonyms: Ezrin phospho T567, Ezrin phospho Thr567, p-Ezrin phospho T567, CVIL, CVL, cytovillin 2 , Cytovillin , DKFZp762H157, FLJ26216, MGC1584, p81, VIL 2 , VIL2, Villin 2, Villin2, EZRI_HUMAN.

Background: The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Gene ID: 7430

Pathways: Maintenance of Protein Location