DOK2 antibody (pTyr139) (AbBy Fluor® 647)

Catalog No. ABIN879001

This Rabbit Polyclonal antibody specifically detects DOK2 in WB, IF (cc) and IF (p). It exhibits reactivity toward Mouse.

Quick Overview for DOK2 antibody (pTyr139) (AbBy Fluor® 647) (ABIN879001)

Target: DOK2

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK2 antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-DOK2 Antibody (AbBy Fluor® 647)

Binding Specificity: pTyr139

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human p56Dok2 around the phosphorylation site of Tyr139

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DOK2

Target: DOK2

Alternative Name: DOK2

Background:

Synonyms: DOK2 Tyr139, p-DOK2 Tyr139, Docking protein 2 56 kDa, Docking protein 2 antibody DOK 2, DOK R, Downstream of tyrosine kinase 2, p56dok 2, p56dok 2, p56DOK, p56dok2

Background: The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]

Gene ID: 9046