ALOX12 antibody (AbBy Fluor® 488)

Catalog No. ABIN882231

This anti-ALOX12 antibody is a Rabbit Polyclonal antibody detecting ALOX12 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for ALOX12 antibody (AbBy Fluor® 488) (ABIN882231)

Target: ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALOX12 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB)

Product Details anti-ALOX12 Antibody (AbBy Fluor® 488)

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 12 Lipoxygenase

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ALOX12

Target: ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))

Alternative Name: Alox12/12 Lipoxygenase

Background:

Synonyms: 12 Lox, 12S lipoxygenase, 12S LOX, Alox 12, Alox12, Alox12L, Alox15, Arachidonate 12 lipoxygenase 12S type, Arachidonate 12 lipoxygenase, Arachidonate 12 lipoxygenase leukocyte type, Arachidonate 12 lipoxygenase, 12S type, Arachidonate 12 lipoxygenase, leukocyte type, EC1.13.11.31, LOG 12, LOG12, Platelet type 12 lipoxygenase, Platelet type lipoxygenase 12, P-12-LOX.

Background: 12 Lipoxygenase is a non heme iron containing dioxygenase which stereospecifically incorporates molecular oxygen into cis,cis-1,4-pentadiene containing polyunsaturated fatty acids. Murine leukocyte 12 Lipoxygenase oxidizes arachidonic acid to 12(S)-HpETE and 15(S)-HpETE in a ratio of 3:1. Murine leukocyte 12 Lipoxygenase is a 75 kDa protein which is 58 % homologous to murine platelet 12 Lipoxygenase, and 70 % homologous to porcine leukocyte 12 Lipoxygenase.

Gene ID: 239

Pathways: Positive Regulation of Endopeptidase Activity