ANKRD1 antibody (AA 185-319) (Cy5)

Catalog No. ABIN882658

This Rabbit Polyclonal antibody specifically detects ANKRD1 in WB, IF (cc) and IF (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for ANKRD1 antibody (AA 185-319) (Cy5) (ABIN882658)

Target: ANKRD1 (Ankyrin Repeat Domain 1 (Cardiac Muscle) (ANKRD1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKRD1 antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ANKRD1 Antibody (Cy5)

Binding Specificity: AA 185-319

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANKRD1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ANKRD1

Target: ANKRD1 (Ankyrin Repeat Domain 1 (Cardiac Muscle) (ANKRD1))

Alternative Name: ANKRD1

Background:

Synonyms: ALRP, CARP, C-193, CVARP, MCARP, bA320F15.2, Ankyrin repeat domain-containing protein 1, Cardiac ankyrin repeat protein, Cytokine-inducible gene C-193 protein, Cytokine-inducible nuclear protein, ANKRD1, C193, HA1A2

Background: May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.

Gene ID: 27063

UniProt: Q15327

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Response to DNA Damage Stimulus