ANKRD1 antibody (AA 185-319) (HRP)

Catalog No. ABIN882666

This anti-ANKRD1 antibody is a Rabbit Polyclonal antibody detecting ANKRD1 in WB, ELISA, IHC (p) and IHC (fro). Suitable for Mouse and Rat.

Quick Overview for ANKRD1 antibody (AA 185-319) (HRP) (ABIN882666)

Target: ANKRD1 (Ankyrin Repeat Domain 1 (Cardiac Muscle) (ANKRD1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKRD1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ANKRD1 Antibody (HRP)

Binding Specificity: AA 185-319

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANKRD1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ANKRD1

Target: ANKRD1 (Ankyrin Repeat Domain 1 (Cardiac Muscle) (ANKRD1))

Alternative Name: ANKRD1

Background:

Synonyms: ALRP, CARP, C-193, CVARP, MCARP, bA320F15.2, Ankyrin repeat domain-containing protein 1, Cardiac ankyrin repeat protein, Cytokine-inducible gene C-193 protein, Cytokine-inducible nuclear protein, ANKRD1, C193, HA1A2

Background: May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells.

Gene ID: 27063

UniProt: Q15327

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Response to DNA Damage Stimulus