SH3GLB1 antibody (AA 151-250) (Biotin)

Catalog No. ABIN884992

This Rabbit Polyclonal antibody specifically detects SH3GLB1 in WB, ELISA, IHC (p), IHC (fro). It exhibits reactivity toward Human.

Quick Overview for SH3GLB1 antibody (AA 151-250) (Biotin) (ABIN884992)

Target: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3GLB1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SH3GLB1 Antibody (Biotin)

Binding Specificity: AA 151-250

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Bif1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SH3GLB1

Target: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Alternative Name: Bif1

Background:

Synonyms: Bax interacting factor 1, Bax-interacting factor 1, B 1, B-1, CGI 61, Endophilin B1, Endophilin-B1, SH3 domain GRB2 like endophilin B1, SH3 domain-containing GRB2-like protein B1, Sh3glb1, SH3p13, SHLB1_HUMAN.

Background: May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion.Tissue specificity: Highly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain, colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes.

Gene ID: 51100

Pathways: Autophagy