Biglycan antibody (AA 101-200) (Biotin)

Catalog No. ABIN885014

The Rabbit Polyclonal anti-Biglycan antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect Biglycan in samples from Human, Rat, Mouse and Rabbit.

Quick Overview for Biglycan antibody (AA 101-200) (Biotin) (ABIN885014)

Target: Biglycan (BGN)

Reactivity: Human, Rat, Mouse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Biglycan antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Biglycan Antibody (Biotin)

Binding Specificity: AA 101-200

Cross-Reactivity: Human, Mouse, Rabbit, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Biglycan

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Biglycan

Target: Biglycan (BGN)

Alternative Name: Biglycan

Background:

Synonyms: PGI, DSPG1, PG-S1, SLRR1A, Biglycan, Bone/cartilage proteoglycan I, BGN

Background: The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with several proteins involved in muscular dystrophy, including alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex.

Gene ID: 633

UniProt: P21810

Pathways: Glycosaminoglycan Metabolic Process