BRSK1 antibody (AA 101-200) (Cy5.5)

Catalog No. ABIN885583

This Rabbit Polyclonal antibody specifically detects BRSK1 in IF (cc) and IF (p). It exhibits reactivity toward Rat.

Quick Overview for BRSK1 antibody (AA 101-200) (Cy5.5) (ABIN885583)

Target: BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRSK1 antibody is conjugated to Cy5.5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-BRSK1 Antibody (Cy5.5)

Binding Specificity: AA 101-200

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BRSK1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BRSK1

Target: BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))

Alternative Name: BRSK1

Background:

Synonyms: BR serine/threonine kinase 1, BR serine/threonine protein kinase 1, BR serine/threonine-protein kinase 1, Brain-specic serine/threonine-protein kinase 1, BRSK 1, Brsk1, BRSK1_HUMAN, Protein kinase SAD1A, SAD 1, SAD1, SAD1 kinase, SAD1A, SADB, SadB kinase short isoform, Serine/threonine kinase SAD B,Serine/threonine-protein kinase SAD-B, Synapses of Amphids Defective homolog, FLJ43009, KIAA1811.

Background: Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo.Tissue specificity: Widely expressed, with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle.

Gene ID: 84446