CCDC134 antibody (AA 11-120) (Biotin)

Catalog No. ABIN887167

This Rabbit Polyclonal antibody specifically detects CCDC134 in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for CCDC134 antibody (AA 11-120) (Biotin) (ABIN887167)

Target: CCDC134 (Coiled-Coil Domain Containing 134 (CCDC134))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC134 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CCDC134 Antibody (Biotin)

Binding Specificity: AA 11-120

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC134

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CCDC134

Target: CCDC134 (Coiled-Coil Domain Containing 134 (CCDC134))

Alternative Name: CCDC134

Background:

Synonyms: CC134_HUMAN, ccdc134, coiled-coil domain containing 134, Coiled-coil domain-containing protein 134, dJ821D11.3, FLJ22349, MGC21013.

Background: Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein, BCR-Abl, a potent cell proliferation activator found in several types of leukemia. CCDC134 (coiled-coil domain containing 134), also known as MGC21013 or FLJ22349, is a 229 amino acid protein encoded by a gene mapping to human chromosome 22.

Gene ID: 79879