CCDC51 antibody (AA 151-250) (HRP)

Catalog No. ABIN887860

This Rabbit Polyclonal antibody specifically detects CCDC51 in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Mouse.

Quick Overview for CCDC51 antibody (AA 151-250) (HRP) (ABIN887860)

Target: CCDC51 (Coiled-Coil Domain Containing 51 (CCDC51))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC51 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CCDC51 Antibody (HRP)

Binding Specificity: AA 151-250

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC51

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CCDC51

Target: CCDC51 (Coiled-Coil Domain Containing 51 (CCDC51))

Alternative Name: CCDC51

Background:

Synonyms: CCD51_HUMAN, CCDC51, Coiled-coil domain-containing protein 51, FLJ12436, RGD1311466, AI551049, 5730568A12Rik.

Background: The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC51 (coiled-coil domain containing 51) is a 411 amino acid multi-pass membrane protein that exists as two alternatively spliced isoforms. The gene encoding CCDC51 maps to human chromosome 3, which is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Gene ID: 79714