CCDC69 antibody (AA 41-140) (Cy3)

Catalog No. ABIN888080

The Rabbit Polyclonal anti-CCDC69 antibody has been validated for IF (cc), IF (p). It is suitable to detect CCDC69 in samples from Human.

Quick Overview for CCDC69 antibody (AA 41-140) (Cy3) (ABIN888080)

Target: CCDC69 (Coiled-Coil Domain Containing 69 (CCDC69))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC69 antibody is conjugated to Cy3

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CCDC69 Antibody (Cy3)

Binding Specificity: AA 41-140

Cross-Reactivity: Human

Predicted Reactivity: Dog,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC69

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CCDC69

Target: CCDC69 (Coiled-Coil Domain Containing 69 (CCDC69))

Alternative Name: CCDC69

Background:

Synonyms: CCD69_HUMAN, ccdc69, Coiled coil domain containing 69, Coiled-coil domain-containing protein 69.

Background: The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC69 (Coiled-coil domain-containing protein 69) is a 296 amino acid protein that is encoded by a gene which maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Gene ID: 26112