CCDC88B antibody (AA 1271-1476) (AbBy Fluor® 555)

Catalog No. ABIN888255

This anti-CCDC88B antibody is a Rabbit Polyclonal antibody detecting CCDC88B in IF (cc) and IF (p). Suitable for Human.

Quick Overview for CCDC88B antibody (AA 1271-1476) (AbBy Fluor® 555) (ABIN888255)

Target: CCDC88B (Coiled-Coil Domain Containing 88B (CCDC88B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC88B antibody is conjugated to AbBy Fluor® 555

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CCDC88B Antibody (AbBy Fluor® 555)

Binding Specificity: AA 1271-1476

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC88B/BRLZ

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CCDC88B

Target: CCDC88B (Coiled-Coil Domain Containing 88B (CCDC88B))

Alternative Name: CCDC88B

Background:

Synonyms: Brain leucine zipper domain containing protein, Brain leucine zipper domain-containing protein, Brain leucine zipper protein, BRLZ, CC88B_HUMAN, CCDC 88, CCDC 88B, Ccdc88b, Coiled coil domain containing 88, Coiled coil domain containing protein 88B, Coiled-coil domain-containing protein 88B, DKFZp434G0920, FLJ00354, FLJ37970, HkRP 3, HkRP3, Hook related protein 3, Hook-related protein 3.

Background: HkRP3, also known as CCDC88B (coiled-coil domain-containing protein 88B) or BRLZ (brain leucine zipper domain-containing protein), is a 1,476 amino acid protein that belongs to the CCDC88 family. Members of the hook-related protein family are characterized by the presence of a C-terminal hook-related domain and an N-terminal potential microtubule binding domain. HkRP3 may be involved in the linkage of various organelles to microtubules, and exists as six alternatively spliced isoforms. The gene encoding HkRP3 maps to human chromosome 11q13.1 and mouse chromosome 19 A. Chromosome 11 houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Gene ID: 283234