NCR3 antibody (PE-Cy5.5)

Catalog No. ABIN889058

The Rabbit Polyclonal anti-NCR3 antibody has been validated for FACS. It is suitable to detect NCR3 in samples from Human, Rat and Dog.

Quick Overview for NCR3 antibody (PE-Cy5.5) (ABIN889058)

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Reactivity: Human, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCR3 antibody is conjugated to PE-Cy5.5

Application: Flow Cytometry (FACS)

Product Details anti-NCR3 Antibody (PE-Cy5.5)

Cross-Reactivity: Human

Predicted Reactivity: Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NCR3

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NCR3

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Alternative Name: NCR3

Background:

Synonyms: 1C7, MALS, CD337, LY117, NKp30, Natural cytotoxicity triggering receptor 3, Activating natural killer receptor p30, Natural killer cell p30-related protein, NK-p30, NCR3

Background: Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

Molecular Weight: 22kDa

Gene ID: 259197

UniProt: O14931

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process