CD40 antibody (AA 201-277) (AbBy Fluor® 350)

Catalog No. ABIN889101

This anti-CD40 antibody is a Rabbit Polyclonal antibody detecting CD40 in FACS, WB, IF (p) and IF (cc). Suitable for Human, Mouse and Rabbit.

Quick Overview for CD40 antibody (AA 201-277) (AbBy Fluor® 350) (ABIN889101)

Target: CD40

Reactivity: Human, Mouse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD40 antibody is conjugated to AbBy Fluor® 350

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-CD40 Antibody (AbBy Fluor® 350)

Binding Specificity: AA 201-277

Cross-Reactivity: Human, Mouse, Rabbit

Predicted Reactivity: Rat,Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TNFRSF5

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CD40

Target: CD40

Alternative Name: TNFRSF5

Background:

Synonyms: p50, Bp50, CDW40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, CD40L receptor, CD40

Background: Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.

Gene ID: 958

UniProt: P25942

Pathways: NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints