CHCHD5 antibody (AA 21-110) (HRP)

Catalog No. ABIN890374

This Rabbit Polyclonal antibody specifically detects CHCHD5 in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for CHCHD5 antibody (AA 21-110) (HRP) (ABIN890374)

Target: CHCHD5 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 5 (CHCHD5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHCHD5 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CHCHD5 Antibody (HRP)

Binding Specificity: AA 21-110

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC99

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CHCHD5

Target: CHCHD5 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 5 (CHCHD5))

Alternative Name: CHCHD5

Background:

Synonyms: C2orf9, CHCH5_HUMAN, CHCHD5, chromosome 2 open reading frame, Coiled coil helix coiled coil helix domain containing 5, Coiled-coil-helix-coiled-coil-helix domain-containing protein 5, FLJ39671, MGC11104.

Background: CHCHD5 is a 110 amino acid protein that contains one CHCH domain. The gene encoding CHCHD5 maps to human chromosome 2, which consists of 237 million bases encoding over 1,400 genes and making up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.

Gene ID: 84269