COMMD3 antibody (AA 101-195) (HRP)

Catalog No. ABIN891810

This anti-COMMD3 antibody is a Rabbit Polyclonal antibody detecting COMMD3 in WB, ELISA, IHC (fro) and IHC (p). Suitable for Mouse.

Quick Overview for COMMD3 antibody (AA 101-195) (HRP) (ABIN891810)

Target: COMMD3 (COMM Domain Containing 3 (COMMD3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COMMD3 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-COMMD3 Antibody (HRP)

Binding Specificity: AA 101-195

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COMMD3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for COMMD3

Target: COMMD3 (COMM Domain Containing 3 (COMMD3))

Alternative Name: COMMD3

Background:

Synonyms: BUP, C10orf8, COMM domain-containing protein 3, Protein Bup, Protein PIL, COMMD3

Background: May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (PubMed:23637203).

Gene ID: 23412

UniProt: Q9UBI1