FAHD2A antibody (AA 121-230) (Biotin)

Catalog No. ABIN896020

This Rabbit Polyclonal antibody specifically detects FAHD2A in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for FAHD2A antibody (AA 121-230) (Biotin) (ABIN896020)

Target: FAHD2A (Fumarylacetoacetate Hydrolase Domain Containing 2A (FAHD2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAHD2A antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-FAHD2A Antibody (Biotin)

Binding Specificity: AA 121-230

Predicted Reactivity: Human,Mouse,Rat,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAHD2A

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FAHD2A

Target: FAHD2A (Fumarylacetoacetate Hydrolase Domain Containing 2A (FAHD2A))

Alternative Name: FAHD2A

Background:

Synonyms: CGI 105, FAH2A_HUMAN, FAHD 2A, FAHD2A, Fumarylacetoacetate hydrolase domain containing 1, Fumarylacetoacetate hydrolase domain containing 2A, Fumarylacetoacetate hydrolase domain containing protein 2A, Fumarylacetoacetate hydrolase domain-containing protein 2A.

Background: The FAH family contains two highly homologous 314 amino acid proteins, designated FAHD2A (fumarylacetoacetate hydrolase domain-containing protein 2A) and FAHD2B (fumarylacetoacetate hydrolase domain-containing protein 2A). FAHD2A and B utilize calcium and magnesium as cofactors, and may possess hydrolase activity. The genes encoding FAHD2A/B map to human chromosome 2, the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome, is also associated with mutations to chromosome 2.

Gene ID: 51011