FAIM antibody (AA 1-100) (FITC)

Catalog No. ABIN896027

The Rabbit Polyclonal anti-FAIM antibody has been validated for IF (cc) and IF (p). It is suitable to detect FAIM in samples from Zebrafish (Danio rerio).

Quick Overview for FAIM antibody (AA 1-100) (FITC) (ABIN896027)

Target: FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAIM antibody is conjugated to FITC

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-FAIM Antibody (FITC)

Binding Specificity: AA 1-100

Cross-Reactivity: Zebrafish (Danio rerio)

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAIM1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FAIM

Target: FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))

Alternative Name: FAIM1

Background:

Synonyms: FAIM 1, FAIM, Fas apoptotic inhibitory molecule 1, Fas apoptotic inhibitory molecule, FAIM1_HUMAN.

Background: FAIM1 (or Fas Apoptotic Inhibitory Molecule 1) is a recently discovered negative regulator of apoptosis. FAIM1 has no significant regions of homology to other gene products that modulate Fas killing. It plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Overexpression of FAIM1 diminishes sensitivity to Fas mediated apoptosis of B and non B cell lines. FAIM1 is highly evolutionarily conserved and is widely expressed in murine tissues, suggesting that FAIM1 plays an important role in cellular physiology.

Gene ID: 55179